Breaking Barriers: Advancing Endometrial Cancer Research

Endometrial cancer is the most common gynecologic cancer in the United States, and its growing incidence calls for urgent action. Despite advances in uterine and endometrial cancer treatment, this condition continues to present significant challenges, such as being significantly underfunded and underdiagnosed, impacting thousands of women each year.

ECRF is dedicated to breaking through these barriers with focused research, support, and advocacy.

Reasons for Starting the Endometrial Cancer Research Foundation

Rising Incidence and Mortality Rates in Endometrial Cancer

Rising Incidence & Mortality Rates

Endometrial cancer is on the rise, and the statistics are alarming and have shown a concerning trend.

  • 69,120 new cases are projected in the U.S. in 2025. By 2030, the number of cases are projected to almost double.

  • Approximately 13,860 women are estimated to die of endometrial cancer in 2025.

  • Death rates for endometrial cancer have been increasing by 1.5% annually over the past decade.

These numbers are a call to action—there’s an urgent need for more research funding and awareness to combat the growing impact of this condition.

Racial and Ethnic Disparities in Endometrial Cancer

Racial and Ethnic Disparities

Significant disparities exist in the incidence and mortality rates of endometrial cancer across different racial and ethnic groups.

  • Non-White women experience higher incidence rates than White women.

  • African American women face disproportionately higher mortality rates, even when socioeconomic factors are considered.

ECRF is committed to advancing equitable research and healthcare access for women from all backgrounds.

The Need for Targeted Research in Endometrial Cancer

The Need for Targeted Research

Endometrial cancer is associated with various risk factors, including hormonal factors, reproductive factors, and genetic predispositions like Lynch syndrome

  • Risk factors include nulliparity, early menarche, late menopause, obesity, and postmenopausal estrogen use.

  • Women with Lynch syndrome face up to 60% greater risk.

Focused research is crucial to understanding these factors and developing targeted prevention and treatment. We prioritize studies on specific risks and genetic links

Supporting Women and Families | Endometrial Cancer Research Foundation

Supporting Women and Families

We believe support extends beyond medical treatment. That’s why ECRF is committed to providing support to women and families:

  • Educational resources to empower patients and families with the knowledge they need to navigate their journey.

  • Support networks to connect patients, caregivers, and advocates to one another.

  • Advocacy initiatives to push for increased funding, better policy, and improved patient care.

We are here to ensure that every woman and their loved ones affected by endometrial cancer feel heard, informed, and empowered throughout their journey.

Advancing Treatment and Prevention in Endometrial Cancer

Advancing Treatment and Prevention

The ultimate goal of ECRF is to change the course by providing advanced treatment options and developing effective prevention strategies: 

  • Funding innovative research projects to identify new treatments and therapies.

  • Promoting clinical trials to test and validate promising new approaches.

  • Developing public health initiatives to educate women about risk factors and prevention methods.

Through research and advocacy, we aim to reduce endometrial cancer and improve women’s lives worldwide.